medicine
Scientists used a DNA-snipping enzyme called Cas9 to cut out the virus.
The cell’s gene repair machinery then takes over, soldering the loose ends of the genome back together – resulting in a virus-free cell.
Process could also be a cure for other latent infections, researchers say.
On this day in #History; #Viagra turned men into Homewreckers and Holewreckers. #medicine #ED #sex #quote #lol #bbc #cockinasock #xxx #instagay
I am $200 away from reaching my Goal!!!
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Dr. Deborah Persaud of Johns Hopkins University today described the first documented case of a child being cured of HIV. The landmark findings were announced at the 2013 Conference on Retroviruses and Opportunistic Infections in Atlanta, GA.
The Canadian scientist who first discovered that grapefruit can alter certain prescription drug levels in the body has released an updated list of 85 medications that may cause such reactions, 43 of which can cause fatal interactions, The New York Times reports. A clinical pharmacologist at the Lawson Health Research Institute in London, Ontario, David Bailey, PhD, updated his list to reflect releases of new medications over the past four years. The list includes drugs to treat HIV, high cholesterol and cancer, as well as immunosuppressants, psychotropic medications, synthetic opioids, birth control and estrogen.
How often such reactions occur is up for debate, but Bailey stresses that however rare they may be, anyone taking prescription medication and consuming grapefruit juice or grapefruit, as well as pomelo, lime and marmalade, should consult the list of drugs and monitor for symptoms that may indicate a side effect of the combination. Timing of grapefruit consumption is not relevant; it must be avoided entirely to avoid the potential interaction.
To see the full list of medications, click here.
To read the New York Times report, click here.
“My most courageous self, the best man that I’ll ever be, lived more than two decades ago during the first years of a horrific plague… I miss the man I was forced to become.”
– “Once, When We Were Heroes,” 2007
AIDS did not kill Spencer Cox in the first, bloodiest battles of the 1980’s. It spared him that.
The reprieve allowed Spencer’s brilliance as co-founder of the Treatment Action Group(TAG) to forge new FDA guidelines for drug approval and help make effective HIV medications a reality, saving an untold number of lives.
Such triumph by a man still in his twenties might have signaled even greater achievements ahead. Instead, Spencer found himself adrift in the same personal crisis as many of his contemporaries, who struggled for a meaningful existence after years of combating the most frightening public health crisis of modern times.
Gay activists like Spencer were consumed by AIDS for so many gruesome years that many of them were shocked, once the war abated, to see how little around them had changed. Climbing from the trenches, they saw a gay culture that must have seemed ludicrous, packed with the same drug addictions, sexual compulsions and soulless shenanigans that AIDS, in its singular act of goodwill, had arrested for a decade or so.
They found themselves in a world in which no one wants to see battle scars, where intimacy is manufactured on keyboards and web sites, where any sense of community had long since faded from the AIDS organizations and now only makes brief appearances in 12-step meetings, or as likely, in the fraternity of active crystal meth addicts chasing deliverance in a dangerous shell game of bliss and desolation.
The dark allure of meth, a drug so devoured and fetished by gay men today that it is now aleading indicator of new HIV infections, enticed Spencer at some point along the way. The drug is known to whisper empty promises about limitless power and sexual escape, while calming the addict’s ghosts and sorrows for miserably brief periods of time.
When Spencer Cox died on December 18, 2012, in New York City, the official cause of death was AIDS-related complications, which is understandable if post-traumatic stress, despair and drug addiction are complications related to AIDS.
Spencer believed that this connection exists. His own writings for the Medius Institute for Gay Men’s Health (an organization he co-founded after his work with TAG) focus on exactly the issues that were distressing him personally: Crystal meth abuse. Loneliness. Risk taking. Feelings of confusion after years of accomplishment and purpose.
In retrospect you can read his work and break the private code written between the lines. It spells out “HELP ME.”
Spencer’s life during this period and beyond was difficult, by many accounts. The Medius Institute failed due to a lack of funding, defeating Spencer’s effort to address mental health issues among gay men. His drug addiction spiraled and ebbed and raged again, until he finally retreated to Georgia to live with family for a few years.
When Spencer returned to New York City last September, many of his closest friends had lost track of him. There is uncertainty about his last months, and no evidence that his addiction was active, but what little medication compliance he managed had been abandoned completely, setting the stage for his final hospitalization.
Spencer Cox died without the benefit of the very drugs he had helped make available to the world. He perished from pneumonia, in an ironic clinical time warp that transported him back to 1985. It was as if, having survived the deadliest years of AIDS, having come so close to complete escape, Spencer was snatched up by the Fates in a vengeful piece of unfinished business.
AIDS has always been creative in its cruelty. And it has learned to reach through the decades with the second-hand tools of disillusionment and depression and heart-numbing traumas. Or, perhaps, using the simple weapon of crystal meth, with all of its seductions and deceits.
Yes. There are many complications related to AIDS.
To consider “survivor’s guilt” the culprit behind the death of Spencer Cox is a popular explanation but not necessarily an accurate one. That condition suggests surviving when other, presumably worthier people, did not. Sometimes guilt has nothing to do with it.
For many of our AIDS war veterans, the real challenge today is living with the horror of having survived at all.
Mark
(PHOTO CREDIT: Walter Kurtz)
Antiretroviral options abound for both those who are HIV treatment naive and those who are experienced. This quick-reference chart compares available medication
options, including dosing and dietary restrictions. To learn more about these medications, including possible side effects and drug interactions, log on to AIDSmeds.com.
People with HIV do not pose a significant risk to others!!
Sign the petition below to co-sign the letter from Sir Elton John and David Furnish calling on Florida Governor Rick Scott to not cut HIV med access to those in need.
The full text of the letter can be found here:
http://goo.gl/30MXO
I am #1575 Sun Jun 19 21:56:54 EDT 2011
Where are we in the struggle to end AIDS? How far have we come?
A piece in the New York Times today explores these questions and more, exemplifying the huge amount of work that must go into accurately covering a topic as significant as the AIDS crisis.
It turns out we’ve come a long way in the AIDS epidemic, and much of our generation has no idea how different things were 30-odd years ago. The writer of this article, linked above, also wrote the first New York Times piece about AIDS, when it was thought to be strongly tied to homosexual men.
This piece speaks volumes to journalists’ role in uncovering AIDS. My favorite section:
The epidemic has brought a new focus on the power of epidemiology to identify a disease’s transmission patterns long before discovery of its cause. In the early days, epidemiologists provided the evidence to show that AIDS could be transmitted through contaminated blood transfusions, a fact many blood bank officials initially refused to accept. Later, lessons learned from AIDS were instrumental in helping control tuberculosis and curbing the spread of SARS.
Yet AIDS still presents extraordinary challenges — not least to journalists trying to chronicle the epidemic’s unfolding story, to remind a new generation of the importance of safe sex, and to follow the sometimes halting effort to make effective drugs available to all who need them.
Read the article above to brush up on the history of AIDS and get a feel for what we’re hoping to accomplish soon. This is extremely important work and we need to recognize it.
To think, they called it GRID (gay-related immune deficiency) is appalling. I remember, as kid, that it was also referred to as the Gay Cancer.
